ABSTRACT
Pruritis occurs in about 35% of chronic renal failure patients, and up to 85% of those undergoing dialysis. Our study demonstrates the efficacy of narrow band 310-315, a relatively novel UVB machine in the treatment of uremic patients, since the difference in the number of patients who improved after narrow band UVB and those improved without narrow band UVB therapy was highly significant [P<0.001]. The study also shows that serum and skin phosphorus plays the major role in the pathogenesis of uremic patients and that narrow band UVB reduces serum phosphate level and possibly skin phosphate content thus preventing precipitation of phosphate molecules as magnesium phosphate in skin cells. The latter is responsible for pruritis through irritation of free nerve endings